How to Pronounce Doxepin (Silenor, Sinequan)

DOX-e-pin
IPA: /ˈdɒksɪpɪn/
Brand names: Silenor, Sinequan
DOX e pin
Doxepin is pronounced DOX-e-pin

How do you pronounce Doxepin?

Doxepin is pronounced “DOX-e-pin”. It has 3 syllables: dox – e – pin. The stress falls on the first syllable, “dox”.

How many syllables are in Doxepin?

Doxepin has 3 syllables: dox – e – pin.

What does Doxepin mean?

Doxepin is a tricyclic antidepressant with exceptional antihistamine properties. At low doses (3-6mg), it is FDA-approved as Silenor for insomnia maintenance. At higher doses, it is used as Sinequan for depression and anxiety. Doxepin has broad receptor affinity, blocking H1 histamine receptors (sedating), serotonin reuptake, norepinephrine reuptake, and muscarinic acetylcholine receptors. Also available as a topical cream for itching.

Word Parts

dox- dibenz[b,e]oxepine tricyclic ring structure
-epin epine chemical suffix for tricyclic compounds

Common Mispronunciations

Sometimes said "dox-EH-pin" (wrong stress) or "DOX-a-pin" (wrong middle vowel). The correct stress is on the first syllable with a schwa vowel: DOX-e-pin

Where You'll Encounter This

Psychiatry, sleep medicine, dermatology (topical form)

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