How to Pronounce Colesevelam (Welchol)

koh-leh-SEV-eh-lam
IPA: /koʊ.lɛ.ˈsɛv.ɛ.læm/
Brand name: Welchol
koh leh SEV eh lam
Colesevelam is pronounced koh-leh-SEV-eh-lam

How do you pronounce Colesevelam?

Colesevelam is pronounced “koh-leh-SEV-eh-lam”. It has 5 syllables: koh ‑ leh ‑ sev ‑ eh ‑ lam. The stress falls on the third syllable, “sev”.

How many syllables are in Colesevelam?

Colesevelam has 5 syllables: koh ‑ leh ‑ sev ‑ eh ‑ lam.

What does Colesevelam mean?

Colesevelam is a non-absorbed bile acid sequestrant that binds bile acids in the intestine, reducing their enterohepatic reabsorption and compelling the liver to convert more cholesterol into bile acids. This process lowers LDL cholesterol levels. Uniquely, colesevelam is also FDA-approved to improve glycemic control in adults with type 2 diabetes, making it one of the few drugs with dual lipid-lowering and antidiabetic indications. It does not affect CYP450 enzymes and has limited systemic absorption.

Word Parts

prefix cole- bile (Greek: chole)
suffix -velam polymer resin sequestrant

Common Mispronunciations

Often said "KOH-leh-sev-lam" collapsing to 4 syllables — all 5 syllables should be heard: koh-leh-SEV-eh-lam

Where You'll Encounter This

Hypercholesterolemia, type 2 diabetes. Non-absorbed resin — no systemic side effects but may impair absorption of fat-soluble vitamins and some drugs. Take other medications 4 hours before colesevelam.

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